The monetization issue is probably going to be the catalyst. I can't see people investing the time and money to make videos (unless they are just starting out or are chronically unpopular... *ahem*) only to post them for free on YouTube.
Ad blockers aren't just used to cheat web sites out of money. They have become necessary due to security and device performance issues. I don't enjoy blocking ads but the last time I disabled my ad blocker, my web browser became very, very slow.
We're just going to have to start paying for content so the sites we patronize will have to be budgeted. Personally I don't find YouTube TV valuable so I just subscribe to stuff like VRV and Funimation (maybe Netflix at some point again in the future).
The Internet just isn't safe to allow ads so this is the only viable alternative I can imagine.