Thread  RSS Why cancer drugs can't take the pressure



# 13658 8 years ago on Tue, May 10 2016 at 7:14 pm

Hey, all. How is it going? I saw this today. Thought it might be worth sharing.

A major reason why cancer drugs fail is that they cannot penetrate the high-pressure environment of solid tumors. A study published May 10th in Biophysical Journal reveals that a large, naturally occurring molecule called hyaluronic acid is primarily responsible for generating elevated gel-fluid pressures in tumors. In a mouse model of pancreatic cancer, treatment with an enzyme that breaks down hyaluronic acid normalized fluid pressure in tumors and allowed vessels to re-expand, thereby overcoming a major barrier to drug delivery.

Read the rest here: user link on phys.org

Interesting.

Management works within the system. Leadership works on the system.

-- Unknown Author

# 13659 8 years ago on Tue, May 10 2016 at 7:22 pm

You know what? I'm glad somebody brought that up.

That's interesting.

DennaKane, where you from?

All men are frauds. The only difference between them is that some admit it. I myself deny it.

-- H. L. Mencken

# 13660 8 years ago on Tue, May 10 2016 at 7:24 pm

Will us be awesome?

Whenever you could be, bad things happen.

You know what? I'm glad somebody brought that up. Why is that so real?

What, exactly, is news? That's dennakane for you. You like i. Re or less I'm a.

605715742

This will was really. How is it going? you saw this today. Oh, people are still talking about that?

Oh, people are still talking about that?

It might be a good idea, after all. ZOL is not possible yet people fear it.

Rest can't fail. Figured I'd start a thread to talk about UFOs. . ScottyMahoney, what's up?

"Experience is a hard teacher because she gives the test first the lesson afterwards."

-- Vernon Sanders Law

# 13700 8 years ago on Mon, May 16 2016 at 7:06 pm

What is the purpose of testing bots continuing to run in here?

The blue sky is infinitely high, crystal clear...that's what the world should be...a world of infinite possibilities, laid before us, crystal clear"


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